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Report

2025 U.S. organ and tissue transplants: Estimated costs and utilization, emerging issues, and solutions

13 February 2025

Organ and tissue transplants are a vital but expensive healthcare service in the United States, yet little research measures transplant costs and trends. Milliman’s periodic report offers healthcare stakeholders unique insights into utilization, billed charges, and other key metrics, as well as guidance on emerging issues in the field.

Since the previous edition of the “U.S. organ and tissue transplants” report, the data set has been expanded. It now draws on a wider range of organ and tissue transplantation cost records nationwide, empowering payers, providers, and pharmaceutical companies to make strategic decisions with greater confidence.


Highlights from Milliman’s 2025 U.S. organ and tissue transplants report

2025 PMPM costs based on billed charges*

Patients younger than age 65

$14.43

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up 5.2% annually

Patients 65 and older

$25.42

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up 9.1% annually

*Per member per month (PMPM) costs compared to the 2020 report (which was released before the COVID-19 pandemic)


  Select from the options below to understand how costs vary by organ.


Market-level insights on emerging issues and innovations for transplant stakeholders

Legislation surrounding organ and tissue transplants continues to evolve. So does the medical science, with potential innovations ranging from AI to xenotransplants. As these issues develop, Milliman’s research helps stakeholders assess the implications across the following areas:

  • Benchmarking and contemporary market intelligence
  • Organ transplant distribution and inequalities
  • Organ availability and viability
  • Bone marrow transplant developments

Our research also highlights additional areas of concern, including wait times, survival rates, and donor data, that may be analyzed to reveal their potential impact on procurement, pricing, provider reimbursement, and more.

View our full analysis in the 2025 U.S. organ and tissue transplants report.

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